Testosterone is the main male sex hormone and is 95% produced in the testicles (LeyDig cells) and 5% in the adrenal glands. Testosterone ensures the development and maintenance of typical masculine characteristics such as sex organs, physique, body hair and the voice and the sexual drive. The hormone is important in the production of sperm cells (sertoli cells) and influences sexual functioning (libido). The production of testosterone from the LeyDig cells in the testicles is influenced by the LH hormone from the pituitary gland.
Testosterone deficiency can have various causes:
· Primary: Not function properly of the Leydig cells in the testicles
· Secondary: reduced function of the pituitary gland so that insufficient LH is available to induce the LeyDig cells to produce testosterone.
Testosterone Deficiency Syndrome (TDS)
This is the case at men with a too low testosterone level in the blood. Complaints that may accompany this are: fatigue and lethargy, decrease in muscle strength / mass, poor concentration and memory, mood swings / depression, decrease in libido, erection problems, sleep disorder with sweating and hot fluses, gynecomastia, obesity and osteoporosis.